Tourism Minister Marthinus van Schalkwyk will represent President Jacob Zuma at the wedding of Prince Albert II of Monaco and former SA Olympic swimmer Charlene Wittstock, the presidency announced on Thursday.
Zuma would not be able to attend the wedding as he would be at an African Union assembly session in Equatorial Guinea, the presidency said in a statement.
Zuma extended good wishes to Wittstock as she prepared to assume her responsibilities as a member of a royal family.
The civil ceremony would take place inside the royal palace on Friday and a larger religious ceremony would take place at the palace courtyard on Saturday.
The couple met during a swimming competition in Monaco in 2000.